Mount Pleasant is a neighborhood in the northwestern quadrant of Washington, D.C. It is bounded by Rock Creek Park to the north and west; Harvard Street NW to the south; and 16th Street NW to the east. It is north of Adams Morgan and west of Columbia Heights. It is home to approximately 10,000 people.

The western four-fifths of the neighborhood is a largely wooded residential enclave bounded on two sides by Rock Creek Park, just east of the National Zoo. Structures in this area are primarily row houses of Neoclassical architecture with rear porches, with some subdivided into multiple apartments.The Eighteen Hundred Block Park Road, NW is notable for its ten detached “suburban” houses on terraces overlooking the street. The twelve buildings at 1644–1666 Park Road NW, designed by Appleton P. Clark Jr. in the style of Colonial Revival architecture, were completed in 1906.

The eastern side of the neighborhood, along 16th Street NW and Mount Pleasant Street, is marked by mid-rise apartment buildings. These buildings offer rental apartments, condominiums and housing cooperatives. A four-block commercial corridor with convenience shopping extends along Mount Pleasant Street. It is also walking distance from larger retail developments in Columbia Heights.

The neighborhood is served by the Mount Pleasant Line and the Crosstown Line buses.